HLA Upregulation During Dengue Virus Infection Suppresses the Natural Killer Cell Response
Dengue virus (DENV) is the most prevalent mosquito-borne virus in the world and a major cause of morbidity in the tropics and subtropics.Upregulation of HLA class I molecules has long been considered a feature of DENV infection, yet this has not been evaluated in the setting of natural infection.Natural killer Custom Hoodie (NK) cells, an innate im